Despair Rune

Sources

SirenMonsters95.52%
Cursed ChestItems33.9%
NecromancerThievingper successful stealThieving targets2.75%
Despair RuneRunecraftingLevel 106116 XPPure Essence1Mind Rune2Chaos Rune2Recipes

Uses

Despair WandRunecraftingLevel 1081,308 XPMagic Wand (Elite)10Despair Rune2,000Nature Rune50