| Divine Breaker | Throne of the Herald |
| Doppelganger Strikes | Into the Abyss |
| Double Edged | Base game |
| Double Swipe | Base game |
| Dragon Storm Call | Throne of the Herald |
| Dragonbreath | Base game |
| Drain | Base game |
| Dread Pursuit | Into the Abyss |
| Dreadful Gaze | Into the Abyss |
| Drown | Throne of the Herald |
| Drowsy SporesA regular attack that applies sleep for 1 turn on a hit. | Base game |
| Drowsy SporesAn unavoidable attack that deals 200 damage and applies sleep for 1 turn. | Base game |
| Dual Attack | Base game |
| Dual Lashes | Into the Abyss |
| Earth WallGives the enemy +8% Damage Reduction, +0.20s Attack Interval, and +30% Reflect Damage for 2 of the enemy's turns. | Atlas of Discovery |
| Earth WallGives you +8% Damage Reduction, +0.20s Attack Interval, and +30% Reflect Damage for 2 of your turns. | Atlas of Discovery |
| Echoing Assault | Into the Abyss |
| Echolocation | Into the Abyss |
| Efflorescence | Throne of the Herald |
| Elderwood Poison | Throne of the Herald |
| Eldritch Beam | Into the Abyss |
| Eldritch CurseAn avoidable attack that deals 100% of the enemy's max hit as damage. On a hit, inflicts Eldritch Curse which disables your lifesteal and hitpoint regeneration for 3 of your turns. | Into the Abyss |
| Eldritch CurseAn avoidable attack that deals 100% of your max hit as damage. On a hit, inflicts Eldritch Curse which disables the enemy's lifesteal and hitpoint regeneration for 3 of their turns. | Into the Abyss |
| Eldritch Hunter | Into the Abyss |
| Eldritch MarkerPerform a regular attack. On a hit, inflicts Eldritch Curse which disables your lifesteal and hitpoint regeneration for 3 of your turns. Gives the enemy +20% Accuracy Rating for 3 of the enemy's turns. | Into the Abyss |
| Eldritch MarkerPerform a regular attack. On a hit, inflicts Eldritch Curse which disables the enemy's lifesteal and hitpoint regeneration for 3 of their turns. Gives you +20% Accuracy Rating for 3 of your turns. | Into the Abyss |
| Eldritch Stalker | Into the Abyss |
| Electric Ball | Throne of the Herald |
| Electric Charge | Throne of the Herald |
| Elemental Impact (Burn) | Base game |
| Elemental Impact (Freeze) | Base game |
| Elemental Impact (Frostburn) | Base game |
| Elemental Impact (Stun) | Base game |
| Elusiveness | Base game |
| Emerald Shots | Base game |
| Engulfing VortexAn avoidable attack that deals damage equal to 75% of the enemy's normal damage 10 times over 1.8s. On a hit, gives you +30% Attack Interval for 1 of your turns. | Atlas of Discovery |
| Engulfing VortexAn avoidable attack that deals damage equal to 75% of your normal damage 10 times over 1.8s. On a hit, gives the enemy +30% Attack Interval for 1 of the enemy's turns. | Atlas of Discovery |
| Entangle | Throne of the Herald |
| Eradicating Blast | Atlas of Discovery |
| Ethereal Arrows | Throne of the Herald |
| Ethereal Shots | Throne of the Herald |
| Evil Malice | Atlas of Discovery |
| Explosion | Throne of the Herald |
| Explosive Pulse | Into the Abyss |
| Fallen Light | Base game |
| Fatal Bite | Throne of the Herald |
| Fatal Spike | Throne of the Herald |
| Fearmonger | Into the Abyss |
| Feather Barrier | Throne of the Herald |
| Feather Lance | Throne of the Herald |
Special attacks